DNA paternity test is a test to determine whether a man is the biological father. The working principle of this test lies behind hereditary molecule called DNA. DNA is composed of two strands and one of these strands is inherited to offspring. In other words, each person inherits one of the strands from mother and other strand from father. In paternity DNA test, DNA profiles of father and child are compared with each other and according to the result it is determined if the alleged father is the biological father of the child.
99.9% of DNA shows similarity between people. To get a result from DNA tests, STR markers located on dissimilar locations of DNA are used and reliability increases when the marker number being tested increases. 16 or 21 markers are generally used in most of the laboratories whereas 25 STR markers and 1 sex chromosome-specific marker, totally 26 markers, are tested in our laboratory.
Humans have two sex chromosomes, XX in females and XY in males. One of them is coming from other whereas other is coming from father. Mother has no role in sex determination since she has only X chromosome. On the contrary, sex is determined according to the chromosome coming form father. If father gives X chromosome, child will have XX and be a girl. Or, father gives Y chromosome, child will have XY and be a boy. Unlike other chromosome types, Y chromosome does not undergo a change during transfer from father to son. Thus, if the child is a boy, an indirect paternity test can be performed by using Y-STR when alleged father is not able to or does not want to attend DNA test. Since all men of same family have same Y chromosome, this indirect test can be done with grand-father, paternal uncle or brother if they are certainly relative of alleged father. The most reliable and accurate result can be still obtained with DNA test performed between alleged father and child.
For paternity test, mother does not have to give any sample. However, we are taking sample from mother when the official father is not available to give permission for DNA test. In addition to that, in order to get more precise result or to evaluate the possibility of mixing child in the hospital with another child, it might be necessary to take sample from mother.
To perform paternity DNA test, DNA samples are taken from participants. For successful DNA isolation, blood or mouth swab samples are used. Besides, tooth brush, sperm, freshly cut nail, cigarette stub, beverage straw, electric razor, chewed gum, used napkin, urine, sweat, skin or hair root can also be used. However, it is not always possible to get DNA profile with them. Since it is hard to obtain pure saliva from babies and needle usage for drawing blood, mouth swab is the most ideal sample. Although it is also possible to perform DNA test with blood taken from mother before delivering baby, this method is not used by our laboratories because of ethical concerns.
We as DNA Hospital care speediness and privacy in addition to reliability. After taking permission from test participants (For under 18 years-old children, permissions have to be taken from official parents) and reaching samples to laboratories, we submit your results just in 2 workdays. This time period can be decreased to 1 workdays with our express test service. Because of our privacy policy, 12 digits reference number composed of numbers and letters is given personally so that no one except you can reach your results. By using this reference number, you can receive your results according to your preferences indicated on result receive form. Moreover, for your kits ordered from our website, you can also check your results online through our website.
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